Association between diminished ovarian reserve and recurrent pregnancy loss: a comparative study
Objective. To assess diminished ovarian reserve prevalence in patients with recurrent pregnancy loss.
Patients and methods. Included 100 females were subjected to evaluation for diagnosis of the cause of recurrent pregnancy loss, we divided our patients into 2 groups each group contains 50 patients; the first group included patients with unexplained recurrent miscarriage and the second group included healthy females with no recurrent pregnancy loss that acts as a control group.
Results. The levels of FSH in the recurrent miscarriage group were higher than the control group (P = 0.005). The levels of AMH in the recurrent miscarriage group were lower than the control group (P = 0.002). The levels of LH, E2 and FSH/LH ratio were nearly similar in both groups.
Conclusions. We found that diminished ovarian reserve as denoted by high FSH levels and low AMH levels was associated with higher risk of recurrent pregnancy loss.