Articles

The role of ultrasound findings in detecting infertility in patients with polycystic ovary syndrome

ABSTRACT

Objective. Polycystic ovarian syndrome (PCOS) is women’s most common reproductive disorder in their childbearing years, with an estimated prevalence of 5–10%. In women with PCOS, the chance of having problems, including infertility, insulin resistance, and type 2 diabetes, increases significantly. The role of ultrasound in diagnosing PCOS is clear. In this study, we aimed to assess the diagnostic value of multiple ultrasound manifestations of PCOS in detecting infertility in patients with PCOS.
Materials and Methods. The study enrolled 246 patients with PCOS, of whom 171 (69%) had infertility and 75 (30%) were fertile. Patients underwent ultrasonography between Days 3 and 7 of the menstrual cycle to assess ovarian volume, total follicle count, follicle distribution pattern (peripherally distributed versus randomly distributed), and S/A ratio.
Results. The mean age of patients in the group without fertility problems was 28, and in patients with infertility, it was 31, but the difference was not significantly meaningful. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of ovarian volume higher than 10cc for detecting infertility in patients with PCOS were 92%, 91%, 90%, and 90%, respectively. Our results show that peripherally distributed follicles and an increased ovarian volume of more than 10 cc exhibited the highest sensitivity, specificity, PPV, and NPV in detecting infertility in patients with PCOS compared with other ultrasound findings.
Conclusions. Peripherally distributed follicles and an increased ovarian volume of more than 10 cc could be used as an appropriate screening test for detecting infertility in patients with PCOS.

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