Synchronous ovarian and uterine tumours, case report of an unusual association


Background. Add in the scientific Literature another clinical case of synchronous ovarian and uterine tumours describing what has been observed and done. When these tumours occur simultaneously, the most common origin appears to be endometrial. A better understanding of synchronous genital tumours is still needed by studying as many cases as possible.
Case presentation. The beginning of our clinical case started by accidentally finding the increase in the uterine size and its endometrial thickness. In the pelvic excavation, also, a voluminous neoformation was observed of adnexal origin. It presented as a multiloculated cystic morphology with inside a solid calcific component. There was no free intra-abdominal effusion. The patient performed the dosage of tumour markers in the blood and underwent radiological investigations. Total hysterectomy with bilateral adnexectomy and multiple peritoneal/omental biopsies were performed. The histological report described the presence of four different types of tumours: atypical endometrial hyperplasia/EIN and foci of intraepithelial endometrioid adenocarcinoma (G1), a mucinous cystadenoma, Brenner tumour and omental mesothelial hyperplasia. At 6-month follow-up, through total-body CT, the patient did not show recurrences of the disease. The patient’s clinical history is compatible with the favorable prognosis generally presented by patients with synchronous uterine-ovarian tumours.
Conclusions. Contrary to the Literature, our case appears anomalous in the association of the histotype. This aspect actually makes the clinical case interesting.

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