Pelvic Floor Prolapse and vitamin D levels are we doing enough? A research paper
Objective. Pelvic organ prolapse is a common problem that negatively affects the quality of life of women and requires a wide range of management steps that can involve serious surgical interventions. This study aims to evaluate a possible relation between pelvic organ prolapse presence and severity, and vitamin D levels. We don’t aim to assess the incidence of pelvic floor prolapse in Jordan in this study.
Materials and Methods. This was a cross-sectional study of non-pregnant females with pelvic organ prolapse presented to gynecology outpatient clinics for a 1-year duration. Full clinical history and gynecological evaluation were recorded and correlated to plasma vitamin D levels. An Independent Ttest was used to analyze the possible relationship between vitamin levels and POP. This study was approved by the Ethical Review Committee, High Education Deanship of the Jordan University for Science and Technology. This study adhered to the principles of the Declaration of Helsinki.
Results. One hundred forty women were recruited, with an average age of 42.1 ± 13.3 and a mean parity of 5.73 ± 1.88. The mean vitamin D levels were 12.8 ± 11.4, lower than the international standards. The serum levels of vitamin D were markedly lower in the prolapse group than in the non-prolapse group (p = 0.046). Moreover, lower vitamin D levels correlate with multisite manifestation (p=0.022), rectocele (p = 0.007), and advanced stage (p = 0.053).
Conclusions. The study concluded that patients with pelvic organ prolapse showed lower vitamin D levels than those without prolapse. Moreover, it seems that vitamin D deficiency can be independently correlated to multisite prolapse and advanced grades