Maternal hemodynamic evaluation in anemic patients: a useful tool to possibly prevent maternal-fetal complications

Objective. During pregnancy there is a physiological reduction in the hemoglobin value which is the expression of a discrepant increase between the plasma volume and the increase in erythrocyte mass. The purpose of the study was to evaluate the maternal haemodynamics of anemic patients, highlighting any correlations with adverse maternal-fetal outcomes.
Materials and Methods. We enrolled 78 anemic patients, with Hb levels below 10.5 g/dL, who underwent a non-invasive hemodynamic evaluation using USCOM at hospital admission. The different parameters were compared with a control group characterized by normal Hb.
Results. Anemic patients showed higher HR, TFc, INO, CO and lower RVS, CI than patients with normal values of Hb, as a sign of hyperdynamic circulation (Table 1); while Delivery of Oxygen was the same in both groups.
Conclusions. Anemic patients have an hyperdynamic hemodynamics characterized by higher cardiac output and lower systemic vascular resistances, guaranteeing a delivery of oxygen comparable to controls despite the low hemoglobin levels. Furthermore, shear stress associated with hyperdynamic circulation could favor endothelial damage, explaining the worsening of maternal-neonatal outcomes, in particular the risk of postpartum hemorrhage.

Table of Content: Vol. 35 (Supplement No. 1) 2023 – Conference Proceedings

Remember that the download is free only for personal use. If you want to utilize articles for large distribution, please contact us at