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Maternal and neonatal outcomes of preterm prelabor rupture of membranes in women with and without cervical cerclage: a case control study

ABSTRACT

This study aimed to compare the maternal and neonatal outcome of preterm prelabor rupture of membranes in women with cervical cerclage admitted in a tertiary care unit compared to women without cervical cerclage.
This is a case control study comparing the maternal and neonatal outcome in Omani women presenting with preterm prelabor rupture of membranes (pPROM) in the presence of cervical cerclage and those with pPROM without cerclage  conducted in Sultan Qaboos University hospital from January 2010 to December 2019. The data was collected from the maternal and neonatal register. The Statistical Package for the Social Sciences software  was used to analyze data.
The mean age of women in the cerclage group was 32.6 ± 5.4 and  in no cerclage group was 28.7 ± 6.2 and the mean parity was 1.7 for both groups. The mean gestational age at the time of ruptured membranes was 28.5 ± 5.4 weeks in the cerclage group and 29.8 ± 5.2 weeks in no-cerclage group with no significant difference. The Cerclage was kept in situ in women with ruptured memebranes for a mean period of 2.6 days. Chorioamnionitis complicated 31% of women in the cerclage group compared to 12% in the no-cerclage (p 0.007) with an OR 3.29 (95% CI 1.35-8.00). Sepsis was significantly more prevelnt among newborns born to mothers with Cerclage, 25%  compared to 6.5%  among newborns in the no cerclage group (OR 5.155 95% CI 1.95-13.66).
Chorioamnionitis  and neonatal sepsis was significantly high in the cerclage group with pPROM.

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