Management of thin endometrium by hysteroscopic instillation of platelet rich plasma: a narrative review

ABSTRACT
Objective. One of the prerequisites for successful pregnancy outcome is the endometrial thickness. In subfertile patients undergoing IVF treatment, the minimum endometrial thickness is presumed to be approximately 7 mm or more prior to embryo transfer. For the treatment of a refractory endometrium, instillation of platelet rich plasma in the subendometrial region via hysteroscopy is a newer technique. This study is conducted to evaluate the effectiveness of PRP treatment in cases of thin endometrium.
Materials and Methods. Review of various articles on hysteroscopic instillation of platelet rich plasma was undertaken by searching in the data bases like PubMed, Scopus, EMBASE, Web of Science, Science direct, etc. The studies describing platelet rich plasma instillation and its different techniques including efficacy and their role in achieving clinical pregnancy were included in the present study. We searched studies from January 2000 to January 2022.
Results. Here, in the previous studies, we saw promising results with hysteroscopic Platelet rich plasma instillation in infertile women.
Conclusions. Autologous platelet rich plasma instillation is not associated with any side effects as it is derived from patients own blood. Also, it is cost effective, less invasive, easily available as well as feasible for the specialist.