Foetal growth restriction and maternal hypertensive disorders: a case series from Udine

Objective. This study aimed at investigating the outcomes of foetal growth restriction (FGR) and its association with mater­nal hypertensive disorders.
Materials and Methods. We included in our analysis wom­en with a FGR diagnosis who delivered from 2020 to 2023 at the University Hospital of Udine. Our cases were divided into early-FGR and late-FGR, according to the ISUOG guidelines published in 2020.
Results. Out of 139 women with FGR, 51 had an early FGR, whereas 88 had a late FGR.
Patients with early FGR received the diagnosis at 27 weeks and delivered at 35+4 weeks on average. The mean birthweight was 1,906.6 grams, 62.7% required NICU admission, and 1 newborn died. Almost half women had a caesarean delivery, mostly due to antepartum non-reassuring foetal heart rate sta­tus and Doppler umbilical artery abnormalities (80% of cases).
A total of 88 patients received a late FGR diagnosis. The mean gestational age at diagnosis was 35+1 gestational weeks, while the mean gestational age at delivery was 38 weeks. The mean birthweight was 2,470.5 grams, 19.3% required NICU admis­sion. Most women delivered vaginally (68.1%). Almost one in three women had a caesarean delivery. Interestingly, most cae­sarean deliveries occurred intrapartum (31.8%).
Hypertensive disorders were retrieved in 31.4% cases with early FGR and in 15.9% cases with late FGR. This difference was not statistically significant.
Conclusions. This cases series analysis confirms that ear­ly-FGR is associated with worse perinatal outcomes than late- FGR. The impact of maternal hypertensive disorders on peri­natal outcome is similar among the 2 groups.

Table of Content: Vol. 36 (Supplement No. 1) 2024 – Conference Proceedings

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