Early solitary splenic metastasis of endometrial cancer: a case report and review of literature
Spleen involvement in the patients affected by endometrial cancer is an extremely rare event. The aim of this study is to report a case of early splenic metastasis of endometrial cancer and a systematic literature review to standardize management.
We describe the case of a 59-year-old patient affected by endometrial cancer FIGO stage IA G3 (N0). She developed an isolated splenic recurrence of clear cell adenocarcinoma and underwent to splenectomy and second line chemotherapy. After 55 months the patient is alive without disease.
The literature review highlights an asymptomatic onset and a 24-month recurrence presentation interval. In most cases the FIGO stage at diagnosis is the I and histotype is endometrioid. Treatment is surgery in all cases, followed by chemotherapy in 50% of cases.